";s:4:"text";s:2819:" We tend to think of immunotherapy as “natural”—as a stronger version of our body’s own defense system. For instance, you might have skin reactions at the needle site, which include: Investigating Cancer Immunotherapy Side Effects Researchers aim to better understand, manage the side effects of these new drugs. With the advent of immunotherapy, oncologists and cancer researchers accustomed to the familiar, decades-old set of toxic side effects from chemotherapies and radiotherapy are being challenged with understanding and defining a new set of short-term and long-term side effects, referred to as irAEs, to provide timely and effective remedies to cancer patients experiencing them. Keep this information with you and pass it along to your regular healthcare team when possible. Early recognition is key to their successful management and require prompt initiation of corticosteroids with hospitalisation if necessary. He is now being treated wirh immunotherapy,Durvlumab. One study found that fatigue was the most common side effect, along with fever, chills, nausea, and reactions at the site of the infusion. Less often, they are severe and may even be life-threatening. What are the side effects of immunotherapy? Immunotherapy can cause side effects , many of which happen when the immune system that has been revved-up to act against the cancer also acts against healthy cells and tissues in your body. When immunotherapy side effects show up varies, but most immunotherapy patients dealing with side effects see them in the first weeks to months of treatment. However, immunotherapy can still have side effects. If you have to see another doctor or healthcare team for whatever reason, you should let them know about your immunotherapy, and be sure to take note of any drugs or treatment you receive. New-onset fatigue should always prompt investigations for immune-related thyroid dysfunction or hypophysitis (pituitary gland inflammation) with assessment of blood thyroid function tests (TFTs) and cortisol levels respectively. However, by virtue of stimulating the patient's immune white blood cells, ICI therapy sometimes causes serious side-effects that mimic autoimmune … Research is being done to help identify those for whom immunotherapy may work and those who may have severe side effects. Often, immunotherapy is fairly well tolerated. Until then, however, it is important that patients, caregivers, and clinicians know what to look for and to have an established response plan if a side effect develops. My husband was dx with 3rd stage NSCLC I the lower love of his right lung and also 3 lymph nodes in March of 2019,did combined radiation and chemotherapy and finished it at the end of May.